Usefulness of Ondansetron versus Dexamethasone as Postoperative Antiemetic Prophylaxis during Major Gynecologic Surgery
Keywords:
postoperative nausea and vomiting, dexamethasone, ondansetronAbstract
Introduction: Postoperative nausea and vomiting are an unwanted sequel during the anesthetic recovery stage.
Objective: To evaluate the usefulness of dexamethasone compared with ondansetron for the prevention of postoperative nausea and vomiting after major gynecological surgical procedures, under general orotracheal anesthesia.
Method: A prospective, analytical and observational study was carried out with 84 patients older than 19 years of age, at Miguel Enríquez Hospital Clinical-Surgical Hospital, from October 2018 to September 2019, divided sequentially, in order of arrival at the surgical unit, into two groups. The group 1 was administered dexamethasone (4 mg intravenously), and the group 2 was administered ondansetron (4 mg), 30 min before the end of the surgery.
Results: The average risk of postoperative nausea and vomiting prevailed significantly among patients aged 41-50 years. Excellent and good conditions predominated (p>0.05) in terms of effectiveness of prophylactic treatment. Headache prevailed significantly in the group 2. Most of the patients did not present adverse events.
Conclusions: Ondansetron and dexamethasone are useful for postoperative nausea and vomiting prophylaxis among patients who received major gynecological surgery, under general orotracheal anesthesia, a reason why it is considered a safe treatment, with mild adverse events and easy control.
Downloads
Downloads
Published
How to Cite
Issue
Section
License
Those authors who have publications with this journal accept the following terms:
- They will retain their copyright and guarantee the journal the right of the first publication of their work.
- All the content of the journal is under a license https://creativecommons.org/licenses/by-nc/4.0/deed.es_ES
- It is recommended to the author to insert their articles in recognized preprints serves and introduce their database in server crated to this end.