Evaluation of Acute Pain in Patients with Dermal Burns Treated with Platelet-Rich Plasma

Authors

  • Orlando Bismark Rodríguez Salazar Hospital Universitario Manuel Ascunce Domenech
  • Zaily Fuentes Díaz Hospital Oncológico Maria Curie. Camagüey
  • Tania Puerto Pérez Universidad de Ciencias Médicas de Camagüey
  • Francis Lebrón Mateo Hospital Universitario Manuel Ascunce Domenech
  • José Abraham Medina Navarro Hospital Universitario Manuel Ascunce Domenech

Keywords:

burns, pain, platelet-rich plasma, anesthesia and analgesia, regenerative medicine.

Abstract

Introduction: Advances in the study of pain physiology allow nociceptive modulation.

Objective: To evaluate acute pain in patients with dermal burns treated with platelet-rich plasma.

Methods: An experimental study was conducted in patients with dermal burns at the Hospital Manuel Ascunce Domenech, in the period from July 2018 to July 2021. The study universe consisted of 200 patients. The sample was 60 patients, an amount divided into two groups of 30 each. The experimental group consisted of patients treated with platelet-rich plasma, while the conventional group included patients who received occlusive cure treatment with silver sulfadiazine cream 1 %.

Results: From the fifth day on, the value of the visual analog scale was 3,80 in the experimental group and 4,97 in the conventional group, with the Mann-Whitney U test rejecting the equality between the groups (0.001). The behavior was observed from day 10 and 15.

Conclusions: Platelet-rich plasma contributes to the modulation of acute pain in patients with dermal burns and is amenable to be used in conjuntion with other analgesic treatments, forming multimodal therapies.

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Author Biographies

Orlando Bismark Rodríguez Salazar, Hospital Universitario Manuel Ascunce Domenech

Máster en Urgencias Médicas. Especialista de Primer Grado en Medicina General Integral. Especialista de Segundo Grado en Cirugía Plástica y Caumatología. Profesor Asistente. Investigador Agregado.

Zaily Fuentes Díaz, Hospital Oncológico Maria Curie. Camagüey

Doctora en Ciencias Médicas.

Especialista de I Grado en Medicina General Integral.

Especialista de II Grado en Anestesiología y Reanimación.

Profesor e Investigador Auxiliar. 

Tania Puerto Pérez, Universidad de Ciencias Médicas de Camagüey

Especialista de Primer Grado en Bioestadística. Profesor Auxiliar

Francis Lebrón Mateo, Hospital Universitario Manuel Ascunce Domenech

Especialista de Primer Grado en Cirugía Plástica y Caumatología

José Abraham Medina Navarro, Hospital Universitario Manuel Ascunce Domenech

Especialista de Primer Grado en Cirugía Plástica y Caumatología.

Published

2023-12-01

How to Cite

1.
Rodríguez Salazar OB, Fuentes Díaz Z, Puerto Pérez T, Lebrón Mateo F, Medina Navarro JA. Evaluation of Acute Pain in Patients with Dermal Burns Treated with Platelet-Rich Plasma. Rev Cub Anest Rean [Internet]. 2023 Dec. 1 [cited 2025 Jan. 10];22. Available from: https://revanestesia.sld.cu/index.php/anestRean/article/view/2147

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