Anesthesia in a patient with hereditary angioedema

Authors

  • Carlos Enríquez Fernández Montoya Hospital "Dr. Gustavo Aldeguería Lima"
  • Zhachel Alejandro Redondo Gómez Instituto Nacional de Oncología y Radiobiología
  • Dayné García García Instituto Nacional de Oncología y Radiobiología

Keywords:

angioedema hereditario, deficiencia de C1-INH, anestesia

Abstract

Hereditary angioedema (HAE) is a rare genetic disease caused by an autosomal dominant mutation that results in an alteration of the gene encoding the activated C1 esterase inhibitor protein (C1-INH), causing deficiency or dysfunction of C1-INH. It is characterized by recurrent and self-limited episodes with transient symptoms of swelling without urticaria of subcutaneous tissues, extremities, intestinal wall, genitalia and upper respiratory tract. Involvement of the larynx and glottis may result in death by asphyxia. The perioperative managment is reported of a patient with HAE and a long history of allergies in which the main considerations are related to the prevention of an acute crisis during the perioperative period. This required a preparation with fresh frozen plasma and tranexamic acid days before surgery, which was continued postoperatively, in addition to careful management during the anesthetic procedure.

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Author Biographies

Carlos Enríquez Fernández Montoya, Hospital "Dr. Gustavo Aldeguería Lima"

Especialista de Primer Grado en Anestesiología y Reanimación. Profesor Instructor. Dpto de Anestesiología y Reanimación

Zhachel Alejandro Redondo Gómez, Instituto Nacional de Oncología y Radiobiología

Especialista de Primer Grado en Anestesiología y Reanimación. Especialista de Primer Grado en MGI. Profesor Auxiliar. Dpto de Anestesiología y Reanimación.

 

 

Dayné García García, Instituto Nacional de Oncología y Radiobiología

Especialista de Primer Grado en Anestesiología y Reanimación. Profesora Asistente. Dpto de Anestesiología y Reanimación

Published

2022-11-01

How to Cite

1.
Fernández Montoya CE, Redondo Gómez ZA, García García D. Anesthesia in a patient with hereditary angioedema. Rev Cub Anest Rean [Internet]. 2022 Nov. 1 [cited 2024 Dec. 25];21(3). Available from: https://revanestesia.sld.cu/index.php/anestRean/article/view/828