Myocardial protection by ischemic remote conditioning in coronary revascularization

Authors

  • Rudy Hernández Ortega Cardiocentro. Hospital Hermanos Ameijeiras. La Habana https://orcid.org/0000-0002-7306-0018
  • Maria Oslaida Agüero Martínez Cardiocentro. Hospital Hermanos Ameijeiras. La Habana https://orcid.org/0000-0001-8826-4710
  • Osvaldo González Alfonso Universidad de Ciencias Médicas de Villa Clara
  • María Idoris Cordero Escobar Hospital Hermanos Ameijeiras. La Habana
  • Teddy Osmín Tamargo Barbeito Hospital Hermanos Ameijeiras. La Habana

Keywords:

remote ischemic conditioning, ischemia, reperfusion, coronary revascularization, enzymatic parameters, cardiac protection

Abstract

Introduction: A series of short periods of distant ischemia, prior to the major ischemic event, can limit the myocardial damage produced by ischemia or reperfusion.
Objective: To evaluate the usefulness of remote ischemic conditioning in patients scheduled for surgical procedures of coronary revascularization.
Methods: A quasi-experimental, explanatory, comparative study with historical control was conducted in two groups of 247 patients proposed for coronary revascularization. A tourniquet was placed in the right arm in the study group, alternating 3 insufflations with 3 dessufflations with a pressure of 200 mmHg, keeping each for 5 minutes. This procedure was performed before, during and after the major ischemic event, caused by the impingement of the coronary artery.
Results: A significant decrease in enzymatic parameters was achieved. No significant differences were found (p> 0.05) according to a set of variables that represent the initial state of the patients.

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Author Biographies

Rudy Hernández Ortega, Cardiocentro. Hospital Hermanos Ameijeiras. La Habana

Médico, anestesiólogo de primer y segundo grado verticalizado en anestesia cardiovascular, profesor auxiliar,master en urgencias médicas y doctor en ciencias médicas

Maria Oslaida Agüero Martínez, Cardiocentro. Hospital Hermanos Ameijeiras. La Habana

Doctora en Ciencias Médicas. Especialista de primer y segundo grado en Anestesiología y Reanimación. Profesora e Investigadora Titular de la Universidad de Ciencias Médicas de La Habana.

Osvaldo González Alfonso, Universidad de Ciencias Médicas de Villa Clara

Máster  en Urgencias Médicas. Profesor Consultante de la Universidad de Ciencias Médicas de Villa Clara.

María Idoris Cordero Escobar, Hospital Hermanos Ameijeiras. La Habana

Doctora en Ciencias. Especialista de primer y segundo grado en Anestesiología y Reanimación. Profesora e Investigadora Titular de la Universidad de Ciencias Médicas de La Habana.

Teddy Osmín Tamargo Barbeito, Hospital Hermanos Ameijeiras. La Habana

Doctor en Ciencias Médicas. Especialista de primer grado en Medicina General Integral y de primer grado en Bioestadística. Profesor e Investigador Titular de la Universidad de Ciencias Médicas de La Habana

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Published

2019-01-04

How to Cite

1.
Hernández Ortega R, Agüero Martínez MO, González Alfonso O, Cordero Escobar MI, Tamargo Barbeito TO. Myocardial protection by ischemic remote conditioning in coronary revascularization. Rev Cub Anest Rean [Internet]. 2019 Jan. 4 [cited 2024 Dec. 22];18(1). Available from: https://revanestesia.sld.cu/index.php/anestRean/article/view/489

Issue

Vol. 18 No. 1 (2019): January - April

Section

Original articles

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