Efficacy of Meperidine as a Subarachnoid Anesthetic in Bilateral Partial Salpingectomy
Keywords:
Intratecal, subaracnoidea, petidina, salpingectomía., intratecal; subaracnoidea; petidina; salpingectomía.Abstract
Introduction: Intrathecal neuroaxial anesthesia offers multiple benefits, but like any technique, it is not without risks, adverse effects, or complications.
Objective: To evaluate the efficacy of subarachnoid pethidine for bilateral partial salpingectomy.
Methods: A quasi-experimental study was conducted at the Martín Chang Puga Teaching Hospital in Nuevitas, Camagüey, between 2021 and 2023, with a population of 43 patients undergoing elective bilateral partial salpingectomy, who were given intrathecal neuraxial anesthesia. The population was divided into two treatment groups: Group I (control group), in which the conventional anesthetic method was used, and Group II (study group), in which only 50 mg of subarachnoid pethidine was used as the anesthetic agent.
Results: The average age of the patients was 34.3 years. In the study group, 50% achieved a Bromage motor block of 3. The latency time was 5.5 ± 1.2 min, and the time to recovery of muscle tone was 75.8 ± 11.9 min. Twelve hours after surgery, 80% of the patients in the study group reported no pain. There was a lower incidence of pruritus and vomiting in the study group (4.65%; 2.33%).
Conclusions: The use of meperidine alone as an intrathecal anesthetic agent for bilateral partial salpingectomy is effective and safe.
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1. Morante Arias JE, Ulloa Vallejo LV, Luna Martillo ST, Minchala Nieto ID. Anestesia regional neuroaxial. RECIAMUC. 2022 [acceso 01/06/2024];6(4):21-0. Disponible en: https://reciamuc.com/index.php/RECIAMUC/article/view/965
2. Múnera W, Plazas M, Hurtado N, Rubio-Cruz D, Sanabria D. Opportunistic Salpingectomy: Patterns of practice in a group of colombian gynecologists. Rev Chil. Obstet Ginecol. 2020;85(6):617-30. DOI: http://dx.doi.org/10.4067/S0717-75262020000600617
3. Gholinataj A, Baradari AG, Najafi S, Kiabi FH. Comparison of Intravenous Ketamine with Intrathecal Meperidine in Prevention of Post-anesthetic Shivering after Spinal Anesthesia for Lower Limb Orthopedic Surgeries: A Double-blind Randomized Clinical Trial. Ethiop J Health Sci. 2021;31(6):1207-14. DOI: https://doi.org/10.4314/ejhs.v31i6.16
4. Rawal N. Intrathecal opioids for the management of post-operative pain. Best Practice & Research Clinical Anaesthesiology. 2023;37;123-32. DOI: https://doi.org/10.1016/j.bpa.2023.01.001
5. Varona-Rodríguez Y. Eficacia del uso de raquianestesia con meperidina intratecal. Rev Ciencias Médicas. 2022 [acceso 01/06/2024];26(6). Disponible en: http://scielo.sld.cu/scielo.phpscript=sci_arttext&pid=S156131942022000600012&lng=es
6. World Medical Association. World Medical Association Declaration of Helsinki: Ethical Principles for Medical Research Involving Human Subjects. JAMA. 2013;310(20):2191-4. DOI: https://doi.org/10.1001/jama.2013.281053
7. Onay M, Şanal Baş S, Işıker A, Akkemik Ü, Bilir A. Effect of Intrathecal Morphine on Postdural Puncture Headache in Obstetric Anaesthesia. Turk J Anaesthesiol Reanim. 2023];51(4):297-303. DOI: https://doi.org/10.4274/TJAR.2023.221140
8. Jaafarpour M, Taghizadeh Z, Shafiei E, Vasigh A, Sayehmiri K. The Effect of Intrathecal Meperidine on Maternal and Newborn Outcomes After Cesarean Section: A Systematic Review and Meta-Analysis Study. Anesth Pain Med. 2020;10(2):e100375. DOI: https://doi.org/10.5812/aapm.100375
9. Zangoue M, Sabertanha A, Younesi Z. Comparing the Effect of Intrathecal Injection of Meperidine, Meperidine-Bupivacaine, and Bupivacaine Alone on Pain Severity and Hemodynamic Parameters after Elective Cesarean Section. Anesth Pain Med. 2022;12(5):e117090. DOI: https://doi.org/10.5812/aapm-117090
10. Subramani Y, Nagappa M, Kumar K, Fochesato LA, Yunus Chohan MB, Fei Zhu Y, et al. Effect of intrathecal lipophilic opioids on the incidence of shivering in women undergoing cesarean delivery after spinal anesthesia: a systematic review and bayesian network meta- analysis of randomized controlled trials. BMC Anesthesiol. 2020;20(1):214. DOI: https://doi.org/10.1186/s12871-020-01116-5
11. Azemati S, Zarghami A, Jouybar R, Naderi-Boldaji V. Analgesic Characteristics of Bupivacaine Alone and in Combination with Dexmedetomidine or Meperidine in Spinal Anesthesia during Cesarean Section: A Double-Blind Randomized Clinical Trial Study. Pain Res Manag. 2022;2022:5111214. DOI: https://doi.org/10.1155/2022/5111214
12. Fattahi-Saravi Z, Naderi-Boldaji V, Azizollahi A, Azemati S, Asmarian N, Bagher Khosravi M. Adequate Anesthesia and More Effective Analgesia by Adjusted Doses of Bupivacaine during Cesarean Section: A Randomized Double-blind Clinical Trial. Iran J Med Sci. 2023;48(4):393-400. DOI: https://doi.org/10.30476/IJMS.2022.95205.2653
13. Hernández Ortega R, González Alfonso O, Hidalgo Menéndez PA, Marrero Font IM, Rodríguez Álvarez JM, et al. Analgesia subaracnoidea con meperidina en la cirugía ginecológica de pacientes con hipertensión arterial. CorSalud. 2011 [acceso 05/04/2024];3(4):216-23. Disponible en: https://www.medigraphic.com/cgi-bin/new/resumen.cgi?IDARTICULO=50420
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