Sedoanalgesia con midazolam-ketamina en el paciente crítico ventilado mecánicamente

Jonathan Mauricio Quisilema Cadena, Idoris Cordero Escobar, Obdulio González Hernández

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Resumen

La sedoanalgesia en pacientes bajo ventilación mecánica artificial se recomienda para lograr una mejor satisfacción del paciente y prevenir complicaciones. El objetivo de este trabajo fue realizar una revisión bibliográfica sobre la acción sedoanalgésica de la combinación de midazolam-morfina comparado con midazolam-ketamina en pacientes críticos tratados con ventilación mecánica artificial. Se realizó una búsqueda manual y digital en diferentes bases de datos como Scielo, IBECS, MEDLINE, Google Scholar, Cochrane y Wh, con los descriptores en inglés siguientes: sedation, midazolam-ketamine, midazolam-morfina AND mechanical ventilation AND crtical illness "[MeSH Terms]. Se encontró un total de 60 artículos, todos realizados en seres humanos, 32 en los últimos 5 años, pero solo 16 a texto completo. De ellos, 7 eran revisiones sistemáticas sobre el tema y solo 4 ensayos clínicos. Ninguno utilizó la asociación midazolam-ketamina para la sedación. En la revisión realizada no se encontró ningún artículo que informara sobre las ventajas de la asociación midazolam-ketamina en la sedación del paciente crítico ventilado mecánicamente, lo que le confiere novedad a la investigación.

Palabras clave

Sedación; midazolam-ketamina; midazolam-morfina; ventilación mecánica; pacientes críticos

Referencias

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